Parabilis is set to receive $125m, including a $50m upfront payment and a $75m investment, subject to agreed conditions.

The partnership will investigate Helicons as standalone therapies and as components of AHCs for potential new therapies. Credit: Gorodenkoff / Shutterstock.com.

Regeneron Pharmaceuticals has signed a $2.32bn research collaboration with Parabilis Medicines to develop therapeutic candidates leveraging the latter’s Helicon peptide platform, with an emphasis on antibody-Helicon conjugates (AHCs).

Helicons are stabilised, cell-penetrant alpha-helical peptides engineered to interact with intracellular protein targets, including those with flat surfaces unsuitable for traditional small molecule engagement. Discover B2B Marketing That Performs

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