May 18, 2026
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AstraZeneca announced the FDA approved baxdrostat for uncontrolled hypertension as add-on therapy on top of standard care.Baxdrostat (Baxfendy) is the first aldosterone synthase inhibitor approved to treat uncontrolled high blood pressure in people with primary aldosteronism, a hormonal disorder that promotes sodium and water retention, according to a company press release.
May 18, 2026
1 min read
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Aldosterone synthase inhibitor baxdrostat indicated as add-on to other antihypertensives

AstraZeneca’s Baxfendy (baxdrostat) has been approved in the US as a first-in-class aldosterone synthase inhibitor (ASI) for the…

BAXFENDY approved in the US as the first and only aldosterone synthase inhibitor treatment for adults with hypertension

Baxfendy inhibits a blood-pressure-raising enzyme and, according to AstraZeneca executives, is poised to be a “big product” that…

After an impressive phase 3 showing last fall, AstraZeneca’s wager on CinCor Pharma and its aldosterone synthase inhibitor (ASI)…

Trials of baxdrostat have produced ‘exciting’ results for people whose hypertension has proved difficult to control