The head of the CIA flew to Havana on a rare top-level mission to demand “fundamental changes” from Cuba’s regime, as Donald Trump escalates pressure on the communist government to liberalise its economy.

The meeting on Thursday came after the government in Havana said it had run out of diesel and fuel oil supplies vital for power generation as the US has blocked nearly all oil from the island over the past four months.

CIA director John Ratcliffe met officials including Raúl Rodríguez Castro, who has been Havana’s interlocutor in recent talks with the US, as well as interior minister Lázaro Álvarez...

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