Lebanon's prime minister has accused Israel of war crimes after Israeli airstrikes killed one journalist and wounded another in southern Lebanon on Wednesday.

Amal Khalil and Zeinab Faraj were deliberately targeted as they sought shelter in a home after an initial airstrike hit the vehicle in front of them, killing two men, Lebanese officials say.

The officials also accused the Israel Defense Forces (IDF) of intentionally targeting a marked ambulance as it tried to reach the journalists in the village of Tayri.

The IDF denied that it was preventing rescue teams from reaching the area and said it did not target journalists.

Journalists Khalil, 43, who worked for Lebanese newspaper Al-Akhbar, and Faraj, a freelance photographer, were travelling together. The two men who died have not been named by officials.