Christina Applegate has been hospitalized, according to a new report.

The actress, who has been battling the effects of multiple sclerosis since 2021, is currently hospitalized in Los Angeles after being admitted in late March, TMZ reported from "sources with direct knowledge" Thursday, April 16. It's unclear whether her hospitalization is related to her diagnosis.

Applegate's rep Ame Vanlden declined to comment on whether Applegate was hospitalized or her current medical status. "She's had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast," her rep told USA TODAY.

Applegate's "MeSsy" podcast, which she cohosts with fellow actress Jamie-Lynn Sigler who also has multiple sclerosis, went on a short hiatus at the end of March. They announced the podcast would be taking a "short break for the next few weeks" while Sigler and Applegate promoted their books.

The "Married… with Children" star told USA TODAY in late February that she was "sick as a dog" from a viral infection, speaking from bed for an interview about her memoir, "You with the Sad Eyes." She recalled not realizing how difficult it would be unearthing "all of these things that were so unbelievably horrifying in my life," which she has stuffed "into what I call my trauma ball in my stomach."