A fashion segment took an emotional toll on Drew Barrymore on her talk show, where she opened up about how her body insecurities have progressed after having two C-sections.

On the April 6 episode of "The Drew Barrymore Show," the "Charlie's Angels" actress, 51, was moved by the guest Dawn Benwood's journey of losing 75 pounds after being overweight most of her life and trying on tight-fitted clothes.

"I can't get away from the big baggy clothes because it's weird wearing tighter clothes," Benwood said with tears in a pre-taped segment that aired on the episode. "Even now I still look in the mirror, and I know I'm a different size, but I don't see that. I would love to feel confident and be able to go out and not be worried about [wondering] 'Do I look stupid?'"

The talk show host shared how much Benwood's story resonated with her, saying, "I so related. I really did."

"The other day, I was walking down the street, and I've had two C sections, and I'm so wrecked down there that I permanently just, I can't wear a lot of different types of pants," Barrymore said.