In a matter of days, three Americans and one Canadian will set their sights on heading toward the moon for the first time in more than half-a-century.

Yes, robotic U.S. landers have begun to touch down on the moon in recent years. But ever since the Apollo era came to an end in 1972, humans have yet to venture back anywhere near Earth's celestial neighbor.

Now, that's due to change with the launch of a NASA mission known as Artemis 2.

The second under the U.S. space agency's multibillion-dollar Artemis program, the mission is also the first in the renewed lunar campaign with a crew. While those crew members won't be making a lunar landing, their 10-day journey around the moon and back will pave the way for NASA to put boots back on the surface in the years ahead.

Ahead of the Artemis 2 launch, here's everything you need to know about the mission.