As someone who has dedicated decades of their life to finding solutions for the chronic eczema and severely dry skin on my hands, it’s surprising that I only just learned about Gloves in a Bottle, a unique hand lotion that appears to be the gold standard among nurses and other industry workers who frequently wash their hands.Although I’ve yet to put this stuff to the test myself, the first-person testimonials I’ve read attesting to its skin-saving abilities have been incredibly convincing, to say the least. Gloves in a Bottle calls itself a “shielding lotion,” meaning that it “bonds with the outermost layer of skin cells,” according to the brand, to create an invisible film that protects skin from losing vital moisture, while also keeping potential irritants and surfactants out for up to 12 hours, even through hand washing.This type of protection grants compromised skin the ability to restore itself and rebuild its natural barrier so deep cracks, flakiness and irritation can be a thing of the past. Trust me when I say that this is an indispensable allowance for people with skin conditions like eczema, psoriasis and atopic dermatitis.“Every finger tip has had multiple, painful cracks that hurt terribly and bleed quite a bit,” one Amazon customer with chronic eczema wrote. “This stuff works like a dream. I’ve only been using it [for] about three to four days, and the difference is amazing! I can use my fingers again! My hands are nearly completely healed.” This same reviewer claimed that they had previously (and desperately) tried everything from folk remedies to prescription creams, yet nothing managed to accomplish what Gloves in a Bottle did in just a few short days. Another Amazon reviewer who is a hairdresser said the formula worked so well, they no longer needed to use their prescription eczema ointment.“This is only my second day using Gloves In A Bottle, and the pain, cracking, flaking and bleeding has STOPPED,” they said in their review.As someone who has tried the gamut of hand creams and lotions, I’m keenly aware that if the texture is too greasy or feels too obvious on the skin, then I’m not going to use it. Luckily, the makers of Gloves in a Bottle considered this and promise to have created a truly invisible-feeling formula that immediately soaks into the skin, won’t leave slick trails of product on everything you touch and permits you to go about your regular routine, while still having protected and hydrated skin. “It honestly feels like there is nothing on you, and you immediately work on your computer or any other device without smearing lotion residue anywhere. It honestly did last throughout several hand washes and only came off in the shower several hours after I used it,” an Amazon shopper wrote in a review. In terms of ingredients, this lotion contains a few hallmark hydrators and skin softeners like glycerin, a dermatologist-adored humectant, and dimethicone, an emollient that’s responsible for creating the formula’s key shielding power. Some reviewers also acknowledge that the price may seem a little steep when compared to drugstore hand lotions, however, they insist it’s worth it since you only need a small amount, and you don’t need to constantly reapply throughout the day. As I previously mentioned, the sheer number of enthusiastic and convincing words from users of Gloves in a Bottle was overwhelming, but I managed to compile a few below, just in case you need more persuading to grab a bottle from any of the featured links. Promising Amazon reviews:“I wasn’t really sure what to expect I was just looking for a product to help my incredibly dry scaly and cracked hands. This year has been incredibly challenging and I’m not quite sure why but regular cream and lotion and things I used to do just weren’t working. I watched quite a few YouTube dermatologists and many of them recommended this so I figured why not! After one use I am a believer. This product was incredible. For anyone who doesn’t like greasy slimy or even a normal lotion on their hands perhaps because of transfer or just texture you will absolutely love this. It honestly feels like there is nothing on you and you immediately work on your computer or any other device without smearing lotion residue anywhere. It honestly did last throughout several hand washes and only came off in the shower several hours after I used it. May I also add that I only used it one time and this was the effect. I will definitely be recommending this product and buying it again.” — Valerie V. Perez“This truly is the BEST moisturizer I’ve ever used!! I have been battling with psoriasis on my face, arms, and legs for about 3-4 months now and nothing I used would help and I used many different kinds of creams and moisturizers. But I used this stuff for just 4-5 days and my face cleared completely up and my arms and legs are almost completely cleared up as well!! Thank you so much for this product! It has truly changed my life! It really is like having a moisturizing shield on your skin! I will recommend this to everyone I know! Thank you thank you!!” — Christina White“This is absolutely, by far, the best lotion for eczema and atopic dermatitis. I have suffered with eczema since birth and for the last 18 months have not been able to clear it up. Every finger tip has had multiple, painful cracks that hurt terribly and bleed quite a bit. I use cotton liner gloves with lotions and steroid creams and came across this product on Amazon looking for those. I thought I’d give it a try, but I really wasn’t expecting much. Boy was I wrong! This stuff works like a dream. I’ve only been using it about 3-4 days and the difference is amazing! I can use my fingers again! My hands are nearly completely healed. I have tried so many prescriptions, non-prescriptions, folk remedies, boric acid, Apple cider vinegar, crisco.....ive been desperate. This one product did the trick in just a few short days. I wished I had taken a picture of my fingers before using so you could see the difference, but I hate those catty comments women make about posting pics of hands online without a manicure. I have not been able to get a manicure for the last year and a half because it is too painful. If you have severe painful eczema, you will be so glad you tried Gloves In A Bottle.” — shannon miller“Saving my skin! I’m a hairstylist, and have dry skin & eczema (not the best combo!). I saw another hairdresser post about this lotion, and decided to give it a try - IT WORKS! My hands are often wet, and I’m washing them many many times throughout the day. Even with moisturizing constantly, my hands were red, flaky, itchy, and often cracked and bleeding. This is only my second day using Gloves In A Bottle, and the pain, cracking, flaking and bleeding has STOPPED! I only apply a small amount once on clean house when I get to work, and once before I leave. It’s not greasy, has no odor, and lasts through all of my clients’ shampoos and my hand washings. I haven’t even needed to use my exzcema ointment!” — MikeThe original version of this story was published on HuffPost at an earlier date.If you want your hand lotion to be working even harder, here are three of our top retinol hand creams.Gold Bond Age Renew Retinol Overnight body lotionLock in that anti-aging and hydrating goodness with this ultra-moisturizing overnight cream from Gold Bond. The retinol-peptide complex can help to lift, tighten and moisturize skin without leaving you feeling greasy or with the irritation that can commonly accompany retinol usage. Pop it on your hands (and beyond) and start to see and feel the difference. While not explicitly a hand cream, reviewers noted that it is just the right texture for hands and leaves their hands looking and feeling as good as new. Promising review: "It's light and smooth, very comfortable and nonirritating. I use it mostly on my hands and neck. It feels light and very comfortable and it has no scent which is great for those who are sensitive to that. For the price and the amount you get for a body lotion that have great ingredients including retinol and vitamins i say its worth the try and see how much improvement it gives to the look of your hands and/or neck. I havent used it on my other parts of my body since im using a diff product with retinol on my face. They also ship it with tape on the opening so it wouldnt spill out which is great." — EmieNécessaire The Hand retinol repair serumFor a fairly high concentration of retinol, consider this hand serum from Nécessaire. it has 0.25% of retinol alongside peptides, AHAs, amino acids, vitamins and glycerin to hydrate deeply. It's a great option for anyone looking to treat or prevent crepey skin, dark spots, scars and even ragged cuticles. You'll feel like you just stepped out of a nail salon every morning. Promising review: "Absolute wonder! I bought this based on a dermatologist's recommendation, and it really delivers! After a very short time my hands look and feel so much better! I was starting to notice my hands were looking older, and this has really helped." — ROinCoBeauty Pie Super Retinol Hands anti-aging moisture creamGet all the benefits of a deeply moisturizing, rich hand cream with the added power of encapsulated retinol with this Beauty Pie cream. It can help with common signs of hand aging, targeting dark spots, smoothing and elasticity. Throw it on before bed and wake up to baby-soft hands.Promising review: "A must for older hands. Wonderful night time hand treatment for aged hands. Helps with age spots and crepey skin. Also very moisturising without being sticky." — Mary