Jan. 23 (UPI) -- The snowfall and ice from a winter storm is expected to impact much of the United States beginning Friday and has triggered thousands of flight cancellations.

Total flight cancellations within, into or out of the United States for Saturday numbered 2,179, as of Friday, flight-tracking website FlightAware reported.

American Airlines was the most-affected airline, with 583 cancellations and one delay announced, followed by Southwest, which had 497 cancellations and 7 delays on record.

American Airlines subsidiary Envoy Air had another 261 flights canceled and one delay, followed by SkyWest with 176 cancellations and one delay.

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