The San Francisco 49ers (12-5) take on the Seattle Seahawks (14-3) at Lumen Field in Seattle for a divisional round matchup as the stakes get higher in the NFL playoffs.
These NFC Division rivals will face off against each other to determine who will advance to the NFC Championship game. They split their two meetings during the regular-season.
The Seahawks got the best of the 49ers, 13-3, on Jan. 3 in Week 18 of the regular-season to clinch home-field advantage throughout the postseason. The 49ers got them earlier in the season-opener beating Seattle, 17-13, on Sept. 7, 2025.
San Francisco has already upset the Philadelphia Eagles so far this postseason, taking them out of contention with a 23-19 victory in the NFL wild-card round.
In a win-or-go-home contest between the 49ers and Seahawks, football experts and analysts gave their predictions on who would win and make it to the next round.
