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Shares of U.S. medical supplies giant Medline

jumped more than 22% in their debut on the Nasdaq on Wednesday after the biggest initial public offering of the year globally.

The stock opened at $35, up from its $29 IPO price.

The private equity-owned company sold a little over 216 million shares on Tuesday, raising $6.26 billion in an upsized offering that finishes off a strong year for new listings and bolsters optimism about the IPO market in 2026. Shares of Medline will trade under the symbol “MDLN.”