Aircraft erupted into a fireball after takeoff at Louisville international airport, killing at least seven and injuring 11

Dozens of air safety investigators are set to arrive in Kentucky on Wednesday to piece together evidence on how a UPS cargo plane crashed and erupted into a huge fireball, killing at least seven people and injuring a further 11.

At least 28 National Transportation Safety Board agents will start searching for clues about the possible cause of the disaster, which saw the UPS plane crash shortly after takeoff at the Louisville Muhammad Ali international airport, leaving behind a fiery trail of destruction on the ground and a huge plume of black smoke.

The plane, a McDonnell Douglas MD-11, had three crew members on board and crashed around 5.15pm local time on Tuesday, according to the Federal Aviation Administration. It was bound for Honolulu.

So far, seven fatalities and 11 injuries have been reported, although Andy Beshear, Kentucky’s governor, has said he expects this death toll to rise. The UofL Health hospital system said that it is treating 10 patients in relation to the crash, with two of them in critical condition at the hospital’s burn center.