MIAMI, Oct. 1 (UPI) -- Jahmyr Gibbs and De'Von Achane lead my Top-50 fantasy football running back rankings for Week 5 of the 2025 season.
Christian McCaffrey, Jonathan Taylor and Saquon Barkley join Gibbs and Achane inside my Top 5. Omarion Hampton, James Cook, Ashton Jeanty, Derrick Henry and Travis Etienne are my other Top-10 options.
My Top-50 wide receiver rankings for Week 5 can be found here. My waiver-wire and free agent targets for Week 5 are available here.
All of my positional rankings will be updated until Week 5 kickoffs. Players also will be moved out of or adjusted within the rankings based on injuries.
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