Israel has welcomed top US diplomat Marco Rubio just days after President Trump rebuked the country over its unprecedented strike attack against Hamas leaders in Qatar on Tuesday.

It marked Israel's first such strike against US ally Qatar and has put renewed strain on diplomatic efforts to bring about a truce in Gaza.

Before departing for the region on Saturday, the US Secretary of State told reporters that while Trump was 'not happy' about the strike, it was 'not going to change the nature of our relationship with the Israelis'.

But Rubio added that the United States and Israel were 'going to have to talk about' its impact on truce efforts.

Israel's strike in Doha targeted Hamas leaders gathering to discuss a new ceasefire proposal put forward by the United States.