Yemen’s Houthi-run prime minister and several ministers were killed in an Israeli strike on Sanaa, the head of the Houthi Supreme Political Council said Saturday, marking the first attack to kill senior officials.

A number of others were wounded in Thursday's strike, Mahdi al-Mashat added, without providing details.

Israel said Friday that the airstrike had targeted the Iran-aligned group's chief of staff, defense minister and other senior officials and that it was verifying the outcome.

Mashat's statement did not make clear whether the Houthi defense minister was among the casualties.

Ahmad Ghaleb al-Rahwi was appointed as prime minister a year ago, but the de facto leader of the government was his deputy, Mohammed Miftah, who was assigned on Saturday to carry out the prime minister's duties.