PESHAWAR: Pakistan’s National Institute of Health (NIH) reported two new cases of the poliovirus on Monday, taking the total number of cases of the disease reported this year to 25 as Islamabad struggles to stem its spread of the infection.

Polio is a highly infectious and incurable disease that can cause lifelong paralysis. Experts say the only effective protection is through repeated doses of the Oral Polio Vaccine (OPV) for every child under the age of five, alongside timely completion of all routine immunizations.

The two new cases were reported from Pakistan’s southern Sindh province, in a 21-month-old girl from Badin district, and in a 72-month-old girl from district Kohistan in northwestern Pakistan.

“With these detections, the total number of polio cases in Pakistan in 2025 has reached 21–including 13 from Khyber Pakhtunkhwa, six from Sindh, and one each from Punjab and Gilgit-Baltistan,” Pakistan’s polio program said in a statement.

The program said continued detection of polio cases shows that children remain at risk in areas with low vaccine acceptance. It said a Sub-National Polio Vaccination Campaign will take place from Sept. 1-7, targeting more than 28 million children under the age of five, in 99 districts across all provinces and regions.