Results of study suggest orforglipron could be a simpler, cheaper alternative to injections

A daily weight-loss pill has been shown to help patients lose about 12% of their body weight, according to the results of a clinical trial.

The drug, made by the American pharmaceutical company Eli Lilly, is a GLP-1 agonist – a type of medication that helps lower blood sugar levels, reduces appetite and slows digestion.

More than 3,000 people took part in the 72-week study. Those who received the highest dose – 36mg of orforglipron – lost on average 12.4% of their body weight, compared with just 0.9% of the control group.

The trial also showed other health benefits for users, including improvements to cholesterol, blood pressure and heart disease risk.