Israel's defence minister has admitted he does not know where Iran's stockpile of enriched uranium is located after the arch foes traded 12 days of intense strikes, according to Israeli media.

Israel Katz said that the military was unsure of the location of the 400 kilograms of enriched uranium that the UN's nuclear watchdog, the IAEA, claims Tehran has produced.

He also admitted that Israel's Air Force sought to eliminate the Islamic Republic's Ayatollah Ali Khamenei during its 12-day assault this month, but that the opportunity 'did not present itself' after the Supreme Leader disappeared underground.

'Khamenei understood this, went very deep underground, broke off contact with the commanders… so in the end it wasn't realistic,' he told public broadcaster Kan.

Katz's admissions came as Iran's Foreign Minister Abbas Araghchi shut down 'speculation' that Tehran would return to negotiations with the United States over its nuclear programme.