United Nations Secretary-General Antonio Guterres warned Thursday that the U.N. Charter is under unprecedented assault, as the 193-member body marked its 80th anniversary amid Israel’s ongoing genocide in Gaza, carried out in defiance of U.N. resolutions and international law and accompanied by a crippling aid blockade.

"We see an all too familiar pattern: Follow when the Charter suits, ignore when it does not. The Charter of the United Nations is not optional. It is not an a la carte menu. It is the bedrock of international relations," Guterres said.

Countries regularly accuse each other of breaching the Charter, but few face concrete consequences. In recent years, Russia and Israel have been called out by the General Assembly for violating the Charter with their wars in Ukraine and the genocide Gaza Strip, respectively.

Both conflicts still rage. In the past week, Iran accused the United States of violating the Charter with its strikes on Iranian nuclear facilities and the U.S. justified them under the Charter as self-defense.

The United Nations was born out of the end of World War II and the Charter was signed in San Francisco by an initial 50 states on June 26, 1945. It came into force four months later with the aim of saving succeeding generations from war and upholding human dignity and the equal rights of men and women and of nations large and small.