Saturday’s strikes come after Israeli ambassador tells UN ‘we will not stop’ until Iranian nuclear threat eliminated while Iran vows to keep defending itself

Israel and Iran launch new attacks as Tehran says it will not negotiate nuclear programme while under threat

Iran’s Fars news agency has said the Isfahan nuclear facility – one of the country’s biggest – has been targeted in Israel’s latest attacks but there is no leakage of hazardous materials.

Iranian media also said Israel attacked a building in the city of Qom, with initial reports of a 16-year-old killed and two people injured.

Israeli bombing has killed at least 639 people and wounded 1,326, according to Iranian media, while Iranian missiles have killed at least 25 people and wounded hundreds in Israel.