Israel escalated its bombing campaign Sunday by targeting an Iranian defense facility and fuel depots, following overnight missile strikes from Iran that killed at least 10 people, in what officials described as the most intense confrontation between the two rivals to date.

In Tehran, a heavy cloud of smoke billowed over the city after Israeli aircraft struck two fuel depots. For days, Iranians have formed long queues at petrol stations, fearing shortages.

Iranian media later said Israel attacked a facility affiliated with the Defense Ministry in the central city of Isfahan, reporting "possible damage."

U.S. President Donald Trump said Sunday that Washington "had nothing to do" with ally Israel's intense bombardment campaign that was launched early Friday, hitting key military and nuclear sites as well as residential areas.

But Trump threatened to launch "the full strength and might" of the U.S. military if Iran attacks American interests, saying on his Truth Social platform that "we can easily get a deal done between Iran and Israel, and end this bloody conflict!!!"