Karen Read’s fate will soon rest in the hands of Massachusetts jurors – again.

Prosecutors and defense attorneys will begin delivering their closing arguments Friday in Read’s second murder trial over the death of her Boston cop boyfriend John O’Keefe.

Judge Beverly Cannone said she expects to the jury to start deliberating by the end of the day.

Read, 45, is accused of striking O’Keefe with her SUV and then leaving him to die in the snow on the lawn of a friend’s house after the couple got into an argument during a night of heavy drinking on Jan. 29, 2022.

The defense said Read dropped O’Keefe off at the home of their friend and fellow Boston police officer, Brian Albert, and never saw him again. Police, they argued, were biased against Read from the beginning and never investigated evidence suggesting other potential suspects were responsible for O’Keefe’s death.