SEOUL: Airlines cleared out of the airspace over Israel, Iran and Iraq early on Friday after Israel launched attacks on targets in Iran, Flightradar24 data showed, with carriers scrambling to divert and cancel flights to keep passengers and crew safe.

Proliferating conflict zones around the world are becoming an increasing burden on airline operations and profitability, and more of a safety concern.

Six commercial aircraft have been shot down unintentionally and three nearly missed since 2001, according to aviation risk consultancy Osprey Flight Solutions.

Israel on Friday said it targeted Iran’s nuclear facilities, ballistic missile factories and military commanders at the start of what it warned would be a prolonged operation to prevent Tehran from building an atomic weapon.

Tel Aviv’s Ben Gurion Airport was closed until further notice, and Israel’s air defense units stood at high alert for possible retaliatory strikes from Iran.