The US has said it is not involved in Israel's bombardment of Iranian nuclear sites, an escalation that is threatening to send the region deeper into conflict.
Secretary of State Marco Rubio released a statement soon after the strikes began, saying Israel had taken "unilateral action" and warning Iran to not retaliate against the US.
"We are not involved in strikes against Iran and our top priority is protecting American forces in the region," Rubio said. "Let me be clear: Iran should not target U.S. interests or personnel."
While the US has so far publicly distanced itself from the Israeli operation, Iranian state TV was quick to point the finger at Washington, accusing it of being "complicit" in an attack that has "killed children".
The Israeli strikes - dubbed Operation Rising Lion - targeted Iran's nuclear programme and other military sites, according to a statement by the Israel Defence Force.
