Russia unleashed waves of drones and missiles on two Ukrainian cities early Tuesday, killing two and injuring at least 13, Ukrainian officials reported.

Ukrainian President Volodymyr Zelenskyy described the assault as “one of the biggest” since the war began more than three years ago. He said Moscow’s forces launched more than 315 drones, mostly Shaheds, and seven missiles overnight.

“Russian missile and Shahed strikes drown out the efforts of the U.S. and allies to push Russia toward peace,” Zelenskyy wrote, calling for “concrete action” from the U.S. and Europe in response.

In the southern port city of Odesa, a maternity hospital and residential buildings in the city center were hit, regional head Oleh Kiper said. The regional prosecutor’s office confirmed two deaths and nine injuries in the attack.

Four people were injured in the attack on the capital, Kyiv, Mayor Vitali Klitschko said. Associated Press journalists heard explosions and the buzzing of drones around the city for hours.