(Bloomberg) — The 25 people in Roche Holding AG’s (ROG.SW, RHHBY, RHHVF, RHO6.BE, 0QOK.IL) obesity pill study would barely be enough to field both sides of a soccer match. Yet their weight loss added $16.8 billion to the Swiss drugmaker’s market value in a day, only the latest in a series of big share moves based on success in tiny trials.

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